XRCC4 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
XRCC4 Monoclonal Antibody
Catalog Number
RD85505A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Background
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
Q13426
Synonyms
DNA double strand break repair and V(D)J recombination protein XRCC4DNA repair protein XRCC4SSMEDX ray repair complementing defective repair in Chinese hamster cells 4X ray repair cross complementing 4X ray repair cross complementing protein 4X-ray
Calculated MW
38 kDa
Observed MW
38 kDa
Applications
Reactivity
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas