The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam.
Immunogen Information
Immunogen
Synthetic peptide of human TRPM7
Swissprot
Q96QT4
Synonyms
ALSPDCCHAKCHAK1Channel kinase 1Channel-kinase 1Long transient receptor potential channel 7LTrpC-7LTrpC7Transient receptor potential cation channel subfamily M member 7TRP PLIKTRPM7TRPM7