TMED10 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
TMED10 Polyclonal Antibody
Catalog Number
RD253096A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Background
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Immunogen Information
Immunogen
Fusion protein of human TMED10
Swissprot
P49755
Synonyms
1110014C03Rik21 kDa transmembrane trafficking protein21 kDa transmembrane-trafficking proteinMGC102351p23p24 family protein delta 1p24 family protein delta-1p24(DELTA)p24deltap24delta1S31I125S31III125TMED 10Tmed10TMEDATmp 21 ITmp 21Tmp
Calculated MW
25 kDa
Observed MW
Refer to figures
Gene Accession
BC001496
Applications
Research Areas