TAB3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
TAB3 Polyclonal Antibody
Catalog Number
RD75958A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.
Immunogen Information
Immunogen
Recombinant protein of human TAB3
Swissprot
Q8N5C8
Synonyms
MAP3K7IP 3Mitogen-activated protein kinase kinase kinase 7-interacting protein 3NAP1NF-kappa-B-activating protein 1NFkB activating protein 1TAB-3Tab3TAB3TAK1 binding protein 3TAK1-binding protein 3TGF-beta-activated kinase 1 and MAP3K7-binding p
Calculated MW
79 kDa
Gene Accession
BC032526
Applications