SMAD2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
SMAD2 Polyclonal Antibody
Catalog Number
RD71786A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.
Immunogen Information
Immunogen
Synthesized peptide derived from human Smad2 around the non-phosphorylation site of Ser250.
Swissprot
Q15796
Synonyms
Drosophilahomolog ofMADR2hMAD-2HsMAD2JV18JV18-1JV181MADMAD homolog 2MAD Related Protein 2Mad-related protein 2MADH2MADR2MGC22139MGC34440Mother against DPP homolog 2Mothers against decapentaplegic homolog 2Mothers against decapentaplegic
Calculated MW
52 kDa
Observed MW
52 kDa
Applications
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.