Replication protein A 32 kDa subunitis aproteinthat in humans is encoded by theRPA2gene. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
P15927
Synonyms
60S acidic ribosomal protein P1AA409079AI325195AU020965ik:tdsubc_2g1M(2)21CMGC137236OTTHUMP00000004008p32p34RCJMB04_6d17 replication protein A232kDaREPA2Replication factor A protein 2Replication protein A 32 kDa subunitReplication protein A