Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It plays an important role in cell morphology and locomotion.
Immunogen Information
Immunogen
Recombinant protein of human Vinculin
Gene ID
7414
Swissprot
P18206
Synonyms
CMD1WCMH15Epididymis luminal protein 114HEL114MetavinculinMVMVCLOTTHUMP00000019861OTTHUMP00000019862VCLVINCVINCVinculin