The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
Immunogen Information
Immunogen
A synthetic peptide of human Smad3
Gene ID
4088
Swissprot
P84022
Synonyms
DKFZP586N0721DKFZp686J10186hMAD 3hMAD-3hSMAD3HSPC193HST17436JV15 2JV15-2JV152LDS1CLDS3MAD (mothers against decapentaplegic Drosophila) homolog 3MAD homolog 3Mad homolog JV15 2Mad protein homologMADmothers against decapentaplegic homolog 3