Recombinant RENT1 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
Recombinant RENT1 Monoclonal Antibody
Catalog Number
RD87076A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.
Immunogen Information
Immunogen
A synthetic peptide of human RENT1
Gene ID
5976
Swissprot
Q92900
Synonyms
ATP dependent helicase RENT1ATP-dependent helicase RENT1Delta helicaseFLJ43809FLJ46894HUPF 1hUpf1KIAA0221Nonsense mRNA reducing factor 1NORF 1NORF1pNORF 1pNORF1Regulator of nonsense transcripts 1RENT 1RENT1RENT1Smg 2Smg 2 homolog nonsens
Calculated MW
84 kDa
Observed MW
84 kDa
Applications
Reactivity
Conjugation
Unconjugated
Dilution
WB 1:2000-1:3000, IHC 1:50-1:100, IF 1:50-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas