The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes.
Immunogen Information
Immunogen
A synthetic peptide of human Integrin alpha 5
Gene ID
3678
Swissprot
P08648
Synonyms
CD49 antigen-like family member ECD49eFibronectin receptor subunit alphaFibronectin receptoralpha subunitFNRAIntegrin alpha 5 (fibronectin receptor alpha)Integrin alpha-5Integrin alpha-5 light chainIntegrin alpha-FIntegrinalpha 5 (fibronectin r