Recombinant IMPDH2 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
Recombinant IMPDH2 Monoclonal Antibody
Catalog Number
RD87045A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Immunogen Information
Immunogen
A synthetic peptide of human IMPDH2
Gene ID
3615
Swissprot
P12268
Synonyms
IMDH2IMP (inosine monophosphate) dehydrogenase 2IMP dehydrogenase 2IMP oxireductase 2IMPD 2IMPD2IMPDH 2IMPDH IIIMPDH-IIImpdh2Inosine 5' monophosphate dehydrogenase 2Inosine 5' phosphate dehydrogenase 2Inosine monophosphate dehydrogenase type I
Calculated MW
115kDa
Observed MW
150kDa
Applications
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas