Recombinant FTO Monoclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

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Overview

Circle
Product Name
Recombinant FTO Monoclonal Antibody
Catalog Number
RD86943A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG

Background

Circle
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Immunogen Information

Circle
Immunogen
A synthetic peptide of human FTO
Gene ID
79068
Swissprot
Q9C0B1
Synonyms
AlkB homolog 9ALKBH9Alpha-ketoglutarate-dependent dioxygenase FTOAW743446Fat mass and obesity-associated proteinFATSOMOUSEHOMOLOG OFFtoFTOGDFDKIAA1752mKIAA1752Protein fatso
Calculated MW
68kDa
Observed MW
74kDa

Applications

Circle
Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
WB 1:2000-1:5000, IHC 1:50-1:100, IF 1:20-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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