FAK (Focal adhesion kinase 1) is also named as FAK1,FADK,pp125FAK,FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion,migration,proliferation and survival in response to extracellular signals . It also acts as a pivotal signal 'integrator',controlling and coordinating cellular responses that include cell migration,survival,proliferation and,epithelial tissue repair after DNA damage . This protein has 6 isoforms produced by alternative promoter usage and alternative splicing.
Immunogen Information
Immunogen
A synthetic peptide of human FAK
Gene ID
5747
Swissprot
Q05397
Synonyms
FADK 1FADKFAK related non kinase polypeptideFAK1FAK1Focal adhesion kinase 1Focal adhesion KinaseFocal adhesion kinase isoform FAK Del33Focal adhesion kinase related nonkinaseFRNKp125FAKpp125FAKPPP1R71Protein phosphatase 1 regulatory subunit 7