Recombinant CLSTN1 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
Recombinant CLSTN1 Monoclonal Antibody
Catalog Number
RD87020A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
Calsyntenins (calsyntenin-1, -2, -3) compose a family of neuronally expressed proteins that belong to the cadherin superfamily of cell adhesion molecules (PMID: 24966372; 12498782). Calsyntenin-1 (CLSTN1) is a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain. By binding Ca2+, calsyntenin-1 may modulate Ca2+-mediated postsynaptic signals (PMID: 11161476). Calsyntenin-1 is a transmembrane cargo-docking protein for Kinesin-1-mediated vesicular transport (PMID: 16760430). It can mediate axonal transport of the amyloid precursor protein and regulate Aβ production
Immunogen Information
Immunogen
A synthetic peptide of human CLSTN1
Gene ID
22883
Swissprot
O94985
Synonyms
CST-1CSTN1CDHR12PIK3CDALC-ALPHAXB31alphaalcalpha1alcalpha2
Calculated MW
19kDa
Observed MW
19kDa
Applications
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.