Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Immunogen Information
Immunogen
Synthesized peptide derived from the N-terminal region of human ASC
Swissprot
Q9ULZ3
Synonyms
Apoptosis associated speck like protein containing a CARDApoptosis-associated speck-like protein containing a CARDASCASCCARD 5CARD5Caspase recruitment domain containing protein 5Caspase recruitment domain protein 5Caspase recruitment domain-contai