PTEN Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
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Overview

Circle
Product Name
PTEN Polyclonal Antibody
Catalog Number
RD70280A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG

Background

Circle
PTEN (also designated MMAC1),products of tumor suppressor genes,are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors,such as brain,breast,kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the Signal transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa and it is located in the cytosol.

Immunogen Information

Circle
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse PTEN
Swissprot
P60484,O08586
Synonyms
10q23delBZSDECGLM2MGC11227MHAMMMAC1MMAC1 phosphatase and tensin homolog deleted on chromosome 10Mutated in multiple advanced cancers 1Phosphatase and tensin homologPhosphatase and tensin like proteinPhosphatidylinositol 345-trisphosphate 3-ph

Applications

Circle
Reactivity
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:100-1:500
Concentration
480 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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