PSCA Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
PSCA Polyclonal Antibody
Catalog Number
RD253288A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Background
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
Immunogen Information
Immunogen
Synthetic peptide of human PSCA
Swissprot
O43653
Synonyms
PRO 232PRO232Prostate stem cell antigen
Calculated MW
13 kDa
Observed MW
Refer to figures
Gene Accession
Hs.652235
Applications
Research Areas