PRAME Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
PRAME Polyclonal Antibody
Catalog Number
RD252200A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Background
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Fusion protein of human PRAME
Swissprot
P78395
Synonyms
4930534P07RikCancer/testis antigen 130CT130MAPEMelanoma antigen preferentially expressed in tumorsOIP 4OIP-4OIP4OPA interacting protein 4Opa interacting protein OIP4OPA-interacting protein 4PRAMEPRAMEPreferentially expressed antigen in melan
Gene Accession
BC014074
Applications
Research Areas