PKC zeta Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

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Overview

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Product Name
PKC zeta Polyclonal Antibody
Catalog Number
RD71661A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG

Background

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This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.

Immunogen Information

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Immunogen
Synthesized peptide derived from human PKC ζ around the non-phosphorylation site of Thr560.
Swissprot
Q05513
Synonyms
14-3-3-zetaisoformAI098070aPKCzetaC80388EC 2.7.11.13KPCZnPKC zetanPKC-zetaOTTHUMP00000001368OTTHUMP00000044160PKC 2PKC ZETAPKC2PkczPKCZETAPKM-zetaincludedPRKCZProtein kinase C zetaProtein kinase C zeta formProtein kinase C zeta typer1
Calculated MW
68 kDa
Observed MW
80 kDa

Applications

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Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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