Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STA
Immunogen Information
Immunogen
Synthesized peptide derived from human Stat2 around the phosphorylation site of Tyr690
Swissprot
P52630
Synonyms
Homo sapiens interferon alpha induced transcriptional activatorinterferon alpha induced transcriptional activatorISGF 3ISGF3MGC59816P113signal transducer and activator of transcription 2 113kDSignal transducer and activator of transcription 2STAT1