This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
Immunogen Information
Immunogen
Synthesized peptide derived from human PKC δ around the phosphorylation site of Thr507
Swissprot
Q05655
Synonyms
CVID9D14Ertd420eKinase PKC deltaKPCDKPCDMAY 1MAY1MGC49908nPKC deltanPKC-deltaPCKdPKC dPKC deltaPKCDPKCdeltaPRKC DPRKC deltaPrkcdProtein Kinase C deltaProtein kinase C delta typeProtein kinase C delta VIIIProtein Kinase CdeltaTyrosine