This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants
Immunogen Information
Immunogen
Recombinant protein of human PHB
Swissprot
P35232
Synonyms
Epididymis luminal protein 215Epididymis secretory sperm binding protein Li 54eHEL 215HEL S 54ePHBPHBPHB1Prohibitin