P38 Polyclonal Antibody

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Catalog Number
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Overview

Circle
Product Name
P38 Polyclonal Antibody
Catalog Number
RD90680A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG

Background

Circle
MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A,p38MAPK,CSBP1,RK,p38,EXIP,Mxi2,CSBP2,PRKM14,PRKM15,CSPB1,p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.

Immunogen Information

Circle
Immunogen
Recombinant Mouse Mapk14 protein expressed by E.coli
Swissprot
P47811
Synonyms
CSAID Binding Protein 1CSAID binding proteinCSAID-binding proteinCsaids binding proteinCSBP 1CSBP 2CSBPCSBP1CSBP2CSPB1Cytokine suppressive anti-inflammatory drug-binding proteinEXIPMAP kinase 14MAP kinase MXI2MAP kinase p38 alphaMAPK 14MAP
Calculated MW
23kDa
Observed MW
30kDa

Applications

Circle
Reactivity
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000, IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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