This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen Information
Immunogen
Recombinant protein of human OS9
Swissprot
Q13438
Synonyms
Amplified in osteosarcoma 9amplified in osteosarcomaERLEC2OS-9Os9OS9Osteosarcoma amplified 9 endoplasmic reticulum lectinProtein OS-9