NLRP7 Polyclonal Antibody

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Overview

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Product Name
NLRP7 Polyclonal Antibody
Catalog Number
RD76716A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG

Background

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This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen Information

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Immunogen
Synthetic peptide of human NLRP7
Swissprot
Q8WX94
Synonyms
CLR19.4FLJ94610HYDMMGC126470MGC126471NACHTleucine rich repeat and PYD containing 7NACHTLRR and PYD containing protein 7NACHTLRR and PYD domains containing protein 7NACHTLRR and PYD domains-containing protein 7NALP7NALP7NLR familypyrin doma
Gene Accession
NP_001120727

Applications

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Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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