NLRP6 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

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Overview

Circle
Product Name
NLRP6 Polyclonal Antibody
Catalog Number
RD79165A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG

Background

Circle
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen Information

Circle
Immunogen
Synthetic peptide of human NLRP6
Swissprot
P59044
Synonyms
Angiotensin II/vasopressin receptorAVRCLR11.4NACHTleucine rich repeat and PYD containing 6NACHTLRR and PYD containing protein 6NACHTLRR and PYD domains-containing protein 6NAVRNAVR/AVRNLR familypyrin domain containing 6Nlrp6NLRP6Nucleotide
Gene Accession
NP_612202

Applications

Circle
Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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