NLRP4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
NLRP4 Polyclonal Antibody
Catalog Number
RD76978A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes
Immunogen Information
Immunogen
Synthetic peptide of human NLRP4
Swissprot
Q96MN2
Synonyms
Cancer/testis antigen 58CLR19.5CT58FLJ32126NACHTleucine rich repeat and PYD containing 4NACHTLRR and PYD containing protein 4NACHTLRR and PYD domains-containing protein 4NALP4NLR familypyrin domain containing 4NLRP4Nucleotide binding oligome
Gene Accession
NP_604393
Applications
Research Areas