MTP18 (mitochondrial 18 kDa protein), also known as HSPC242, is a 166 amino acid protein essential for cell viability. MTP18 may also have a role in maintaining the integrity of the mitochondrial network. Localized to the mitochonrion, expression of MTP18 is regulated by the PI 3-kinase pathway. Loss of function of MTP18 results in the release of cytochrome c, which subsequently activates the caspase cascade and leads to apoptosis.
Immunogen Information
Immunogen
Recombinant protein of human MTFP1
Swissprot
Q9UDX5
Synonyms
HSPC 242HSPC242Mitochondrial 18 kDa proteinMitochondrial fission process protein 1Mitochondrial fission protein MTP18Mitochondrial protein 18 kDaMTFP1MTFP1MTP 18MTP18