MAGEL2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
MAGEL2 Polyclonal Antibody
Catalog Number
RD76952A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
Immunogen Information
Immunogen
Synthetic peptide of human MAGEL2
Swissprot
Q9UJ55
Synonyms
Mage-l2MAGE-like 2MAGE-like protein 2MAGEL2melanoma antigen-like gene 2NDNL1Necdin like protein 1necdin-like 1nM15ns7Protein nM15PWLS
Gene Accession
NP_061939
Applications
Research Areas