Leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3) was identified by microarray analysis among genes that show differential expression during gastrulation in Xenopus laevis.Lrig3was expressed in the neural plate and neural crest (NC) at neurula stages, and in NC derivatives and other dorsal structures during tailbud stages. A prominent consequence of the morpholino-induced inhibition ofLrig3expression was impaired NC formation, as revealed by the suppression of marker genes, including Slug, Sox9 and Foxd3.
Immunogen Information
Immunogen
Synthetic peptide of human LRIG3
Swissprot
Q6UXM1
Synonyms
Leucine-rich repeats and immunoglobulin-like domains protein 3Leucine-rich repeats- and immunoglobulin-like domains- containing protein 3LIG-3LIG3LRIG1-3Lrig3LRIG3