LIG1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
LIG1 Polyclonal Antibody
Catalog Number
RD82375A
Purification Method
Affinity purification
Isotype
IgG
Host
Background
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant fusion protein of human LIG1 (NP_000225.1).
Gene ID
3978
Swissprot
P18858
Synonyms
LIG1
Applications
Research Areas