KCNJ10 Polyclonal Antibody

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Overview

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Product Name
KCNJ10 Polyclonal Antibody
Catalog Number
RD219262A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG

Background

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KCNJ10 (Potassium Voltage-Gated Channel Subfamily J Member 10) is a Protein Coding gene. Diseases associated with KCNJ10 include Sesame Syndrome and Deafness, Autosomal Recessive 4, With Enlarged Vestibular Aqueduct. Among its related pathways are Inwardly rectifying K+ channels and GABA receptor activation. GO annotations related to this gene include identical protein binding and potassium channel activity. An important paralog of this gene is KCNJ15.This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes.

Immunogen Information

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Immunogen
Fusion protein of human KCNJ10
Swissprot
P78508
Synonyms
inwardly rectifying subfamily J member 10ATP dependent inwardly rectifying potassium channel Kir4.1ATP sensitive inward rectifier potassium channel 10ATP-dependent inwardly rectifying potassium channel Kir4.1ATP-sensitive inward rectifier potassium ch
Gene Accession
BC034036

Applications

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Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
1.08 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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