JAG1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
JAG1 Polyclonal Antibody
Catalog Number
RD79102A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Immunogen Information
Immunogen
Synthetic peptide of human JAG1
Swissprot
P78504
Synonyms
AGSAHDAWSCD 339CD339CD339 antigenHeadturnerhJ1HtuJag 1Jag1JAG1Jagged 1Jagged1 (Alagille syndrome)Jagged1JAGL1MGC104644OTTHUMP00000030278Protein jagged-1Ser 1Ser1Serrate 1Slalom
Gene Accession
NP_000205
Applications
Research Areas