IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Immunogen Information
Immunogen
Synthesized peptide derived from the C-terminal region of human IL8.
Swissprot
P10145
Synonyms
(Ala-IL-8)77(Ser-IL-8)729E3Beta thromboglobulin like proteinC-X-C motif chemokine 8CEF-4chemokineCXC motifligand 8CXCL8EmoctakinGCP-1GCP/IL-8 protein IGCP/IL-8 protein IIGCP/IL-8 protein IIIGCP/IL-8 protein IVGCP/IL-8 protein VGCP/IL-8 pr