IL1RN Polyclonal Antibody

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Overview

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Product Name
IL1RN Polyclonal Antibody
Catalog Number
RD219510A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG

Background

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The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Immunogen Information

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Immunogen
Synthetic peptide of human IL1RN
Swissprot
P18510
Synonyms
DIRAF630041P17RikICIL 1RAICIL-1RAICIL1RAIL-1raIL-1ra3IL-1RNIL1 inhibitorIL1F3IL1RAIL1RAIL1RN (IL1F3)IL1RNInterleukin 1 receptor antagonistInterleukin-1 receptor antagonist proteinIntracellular IL 1 receptor antagonist type IIIntracellular
Gene Accession
NP776214

Applications

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Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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