IkB alpha Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
IkB alpha Polyclonal Antibody
Catalog Number
RD240093A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Immunogen Information
Immunogen
Recombinant human NF-kappa-B inhibitor alpha protein
Swissprot
P25963
Synonyms
I kappa B alphaI-kappa-B-alphaIkappaBalphaIkB-alphaIKBAIKBAIKBalphaMAD 3MAD3NF kappa B inhibitor alphaNFKBIIKB alpha
Applications