IDS Polyclonal Antibody

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Overview

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Product Name
IDS Polyclonal Antibody
Catalog Number
RD219223A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG

Background

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Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome,an X chromosome-linked disease. An internal proteolytic cleavage occurs to produce the mature IDS present in human liver shown to contain a 42 kDa polypeptide N-terminal to a 14 kDa polypeptide..

Immunogen Information

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Immunogen
Fusion protein of human IDS
Swissprot
P22304
Synonyms
Alpha L iduronate sulfate sulfataseAlpha-L-iduronate sulfate sulfataseAW214631IdsIDSIduronate 2 sulfatase 14 kDa chainIduronate 2 sulfatase 42 kDa chainIduronate 2 sulfataseIduronate 2-sulfatase 14 kDa chainIduronate sulfataseIdursulfaseMPS2RP
Gene Accession
BC006170

Applications

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Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
1.02 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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