IDH3G Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

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Overview

Circle
Product Name
IDH3G Polyclonal Antibody
Catalog Number
RD77760A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG

Background

Circle
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit.

Immunogen Information

Circle
Immunogen
Recombinant protein of human IDH3G
Swissprot
P51553
Synonyms
H IDHGIDH gammaIDH3GIDH3GIsocitrate dehydrogenase [NAD] subunit gammaIsocitrate dehydrogenase [NAD] subunit gammamitochondrialIsocitrate dehydrogenase 3 (NAD+) gammaIsocitric dehydrogenaseIsocitric dehydrogenase subunit gammamitochondrialNAD (H
Calculated MW
43 kDa
Gene Accession
BC001902

Applications

Circle
Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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