HNF1A Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

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Overview

Circle
Product Name
HNF1A Polyclonal Antibody
Catalog Number
RD267543A
Purification Method
Affinity purification
Isotype
IgG

Background

Circle
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen Information

Circle
Immunogen
A synthetic peptide of human HNF1A
Gene ID
6927
Swissprot
P20823
Synonyms
HNF1AHNF-1AHNF1IDDM20LFB1MODY3TCF-1TCF1
Calculated MW
12 kDa/27 kDa/30 kDa/43 kDa/55-70 kDa
Observed MW
55 kDa

Applications

Circle
Reactivity
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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