HLA-G Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
HLA-G Polyclonal Antibody
Catalog Number
RD218031A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Background
Human major histocompatibility complex (MHC) antigens,also referred to as human leukocyte antigens (HLA),are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface,where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.
Immunogen Information
Immunogen
Synthetic peptide of human HLA-G
Swissprot
P17693
Synonyms
B2 microglobulinDADB-15K14.8HLA 6.0HLA class I histocompatibility antigen alpha chain GHLA class I histocompatibility antigenalpha chain GHLA class I moleculeHLA GHLA G antigenHLA G histocompatibility antigen class I GHLA G3HLA-GHLA-G histoco
Gene Accession
NP002118
Applications
Research Areas