HCN2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
HCN2 Polyclonal Antibody
Catalog Number
RD78537A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain. Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages.
Immunogen Information
Immunogen
Synthetic peptide of human HCN2
Swissprot
Q9UL51
Synonyms
BCNG-2BCNG2Brain cyclic nucleotide gated channel 2Brain cyclic nucleotide-gated channel 2HAC1Hcn2HCN2Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Gene Accession
NP_001185
Applications
Research Areas