GPR124 Polyclonal Antibody

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Overview

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Product Name
GPR124 Polyclonal Antibody
Catalog Number
RD79047A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG

Background

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TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.

Immunogen Information

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Immunogen
Synthetic peptide of human GPR124
Swissprot
Q96PE1
Synonyms
DKFZp434C211DKFZp434J0911FLJ14390G protein coupled receptor 124G-protein coupled receptor 124GP124GPR 124Gpr124KIAA1531TEM 5TEM5Tumor endothelial marker 5Tumor endothelial marker 5 precursor
Calculated MW
143 kDa
Gene Accession
NP_116166

Applications

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Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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