This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Immunogen Information
Immunogen
Recombinant protein of human FTO
Swissprot
Q9C0B1
Synonyms
AlkB homolog 9ALKBH9Alpha-ketoglutarate-dependent dioxygenase FTOAW743446Fat mass and obesity-associated proteinFATSOMOUSEHOMOLOG OFFtoFTOGDFDKIAA1752mKIAA1752Protein fatso