Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.
Immunogen Information
Gene ID
18646
Swissprot
P10820
Synonyms
Prf1PfpPfnPfn-1CytolysinLymphocyte pore-forming protein