EEF1E1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
EEF1E1 Polyclonal Antibody
Catalog Number
RD218404A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Background
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
O43324
Synonyms
AIMP 3AIMP3Aminoacyl tRNA synthetase complex interacting multifunctional protein 3Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3ARS interacting multifunctional protein 3EEF1E1Elongation factor p18Eukaryotic translation elon
Calculated MW
20 kDa
Observed MW
Refer to figures
Gene Accession
BC005291
Applications
Research Areas