This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen Information
Immunogen
Recombinant Human DNM1L protein expressed by E.coli
Swissprot
O00429
Synonyms
DLP1dnm1lDNM1LDnm1p/Vps1p-like proteindnml1DRP1DVLPDympleDynamin 1 likeDynamin family member proline-rich carboxyl-terminal domain lessDynamin like proteinDynamin related protein 1Dynamin-1-like proteinDynamin-like protein 4Dynamin-like prot