CXCR4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
CXCR4 Polyclonal Antibody
Catalog Number
RD81190A
Purification Method
Affinity purification
Isotype
IgG
Host
Background
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen Information
Immunogen
A synthetic peptide of human CXCR4 (NP_003458.1).
Gene ID
7852
Swissprot
P61073
Synonyms
CD184D2S201EFB22HM89HSY3RRLAP-3LAP3LCR1LESTRNPY3RNPYRNPYRLNPYY3RWHIMWHIMSCXCR4
Calculated MW
39 kDa/40 kDa
Observed MW
36 kDa/70 kDa
Applications
Research Areas