CXCL4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
CXCL4 Polyclonal Antibody
Catalog Number
RD86658A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Background
CXCL4/PF4 is a secreted chemokine that is expressed by megakaryocytes and restrains the coagulation cascade. It is released by activated platelets and regulates Thrombin/Thrombomodulin complexes, activated Protein C (APC), Coagulation Factor Xa, and Fibrin. The anticoagulant heparin neutralizes CXCL4 procoagulant effects. Complexes of heparin and CXCL4 trigger antibody formation that causes the pathological syndrome HITT
Immunogen Information
Immunogen
Recombinant Human CXCL4 protein expressed by E.coli.
Gene ID
5196
Swissprot
P02776
Synonyms
CXCL4SCYB4Platelet factor 4PF-4
Calculated MW
53kDa
Observed MW
53kDa
Applications
Research Areas