This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1.
Immunogen Information
Immunogen
Recombinant protein of human CHMP4B
Swissprot
Q9H444
Synonyms
Charged multivesicular body protein 4bCHM4Bchmp4bChromatin-modifying protein 4bhSnf7-2hVps32-2SNF7 homolog associated with Alix 1SNF7-2Vacuolar protein sorting-associated protein 32-2Vps32-2