CD74 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
CD74 Polyclonal Antibody
Catalog Number
RD240347A
Clonality
Polyclonal
Purification Method
Antigen Affinity Purification
Isotype
IgG
Host
Background
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen Information
Immunogen
Recombinant Human HLA class II histocompatibility antigen gamma chain protein
Swissprot
P04233
Synonyms
CD 74CD74CD74 antigen (invariant polypeptide of major histocompatibility complexclass II antigen-associated)CD74 antigenCD74 moleculeCD74 moleculemajor histocompatibility complexclass II invariant chainCLIPDHLAGGamma chain of class II antigens
Calculated MW
33,26,18 kDa
Observed MW
35 kDa
Applications
Research Areas